PrEP is short for pre-exposure prophylaxis.

It's a once-per-day HIV prevention pill that reduces the risk of contracting HIV by up to 99%. The presence of the medicine in your bloodstream helps stop HIV from taking hold, ensuring you remain HIV-negative.

DoxyPEP is short for doxycycline post-exposure prophylaxis.

It’s a medication that reduces your risk of contracting syphilis, chlamydia and gonorrhea when taken after a potential exposure, such as having unprotected (condomless) anal, oral or vaginal intercourse. You take it within 72 hours after having condomless sex.

PrEP is recommended for persons with the highest risk of HIV infection, including (but not limited to):
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• Men who have sex with men and transgender women

• Heterosexual men and women who have high-risk exposure (such as having a partner with known HIV infection, sex workers, or having sex with a person at high risk for HIV)

• People who inject drugs

DoxyPEP is currently only recommended for men who have sex with men, trans women and other gender-diverse people born with a penis. Additionally, DoxyPEP may be right for you if you:
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• have had a bacterial STI in the past year and have had condomless anal or oral sexual contact with ≥ 1 cis male or trans female partner in the past year

• have a history of syphilis infection

• have had multiple cis male or trans female sex partners in the prior year, even if you have not previously been diagnosed with an STI
  

• If you have health insurance, PrEP is likely available to you for free, as the Affordable Care Act mandates that most health insurance plans provide PrEP at no cost. Freddie partners with Community Based Organizations (CBOs) to provide clinical services related to PrEP – such as consultations, at-home lab tests, and prescription delivery – for free as well.
  

• DoxyPEP is covered by most private insurance plans. Following your assessment, we'll be able to give you more information on your coverage for DoxyPEP.

PrEP: When PrEP is taken daily, it reduces the risk of getting HIV from sex by 99%.

• PrEP is highly effective for anal sex after daily PrEP is taken consistently for seven days.

• PrEP is highly effective for vaginal sex after daily PrEP is taken consistently for 21 days.

Research also suggests PrEP can reduce the risk of getting HIV from drug injection by 84%, but there is less data around its efficacy.

DoxyPEP: Studies show that in people born with a penis, DoxyPEP reduced the risk of chlamydia by 70-89%, syphilis by 73-87%, and gonorrhea by 51-57% when taken as prescribed.